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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast Activation Protein (FAP)' and Ligand = 'BDBM12165'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast Activation Protein (FAP)


(Homo sapiens (Human))
BDBM12165
PNG
(2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbonyl)pyrrolidin-...)
Show SMILES O=C([C@@H]1CN[C@@H](C1)C(=O)N1CCCC1)N1Cc2ccccc2C1
Show InChI InChI=1S/C18H23N3O2/c22-17(21-11-13-5-1-2-6-14(13)12-21)15-9-16(19-10-15)18(23)20-7-3-4-8-20/h1-2,5-6,15-16,19H,3-4,7-12H2/t15-,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



National Health Research Institutes



Assay Description
The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...


Bioorg Med Chem Lett 16: 3268-72 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.037
BindingDB Entry DOI: 10.7270/Q22805V8
More data for this
Ligand-Target Pair