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Found 4 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM287085'
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM287085((E)-8-(3-(4-(but-2-enoyl)piperazin-1-yl)propyl)-6-...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM287085((E)-8-(3-(4-(but-2-enoyl)piperazin-1-yl)propyl)-6-...)
Affinity DataIC50:  2.70nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM287085((E)-8-(3-(4-(but-2-enoyl)piperazin-1-yl)propyl)-6-...)
Affinity DataIC50:  2.70nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM287085((E)-8-(3-(4-(but-2-enoyl)piperazin-1-yl)propyl)-6-...)
Affinity DataIC50:  27.4nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent