BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM339836'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339836
PNG
(US9757364, Compound 34)
Show SMILES COc1cc(OC)c(Cl)c(N(Cc2ncc[nH]2)c2ccc3ncc(cc3n2)-c2cnn(C)c2)c1Cl
Show InChI InChI=1S/C24H21Cl2N7O2/c1-32-12-15(11-30-32)14-8-17-16(29-10-14)4-5-21(31-17)33(13-20-27-6-7-28-20)24-22(25)18(34-2)9-19(35-3)23(24)26/h4-12H,13H2,1-3H3,(H,27,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.29n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair