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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50197691'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (human))
BDBM50197691
PNG
(CHEMBL3891894)
Show SMILES Cc1nc2ccc(cc2[nH]1)-n1ncc(C(=O)c2cc3cc(CN4CCOCC4)ccc3[nH]2)c1N
Show InChI InChI=1S/C25H25N7O2/c1-15-28-21-5-3-18(12-22(21)29-15)32-25(26)19(13-27-32)24(33)23-11-17-10-16(2-4-20(17)30-23)14-31-6-8-34-9-7-31/h2-5,10-13,30H,6-9,14,26H2,1H3,(H,28,29)
PDB
MMDB

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a



Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assay


J Med Chem 59: 10586-10600 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV
More data for this
Ligand-Target Pair