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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50197709'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (human))
BDBM50197709
PNG
(CHEMBL3984621)
Show SMILES Nc1c(cnn1-c1cc(O)ccc1Cl)C(=O)c1cc2cc(CN3CCOCC3)ccc2[nH]1
Show InChI InChI=1S/C23H22ClN5O3/c24-18-3-2-16(30)11-21(18)29-23(25)17(12-26-29)22(31)20-10-15-9-14(1-4-19(15)27-20)13-28-5-7-32-8-6-28/h1-4,9-12,27,30H,5-8,13,25H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20n/an/an/an/an/an/a



Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assay


J Med Chem 59: 10586-10600 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV
More data for this
Ligand-Target Pair