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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM335676'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM335676
PNG
(US9737544, Compound 5)
Show SMILES COc1cc(OC)cc(c1)C(\O)=C1\C=Cc2ncc(nc2N1CCO)-c1cnn(C)c1
Show InChI InChI=1S/C22H23N5O4/c1-26-13-15(11-24-26)19-12-23-18-4-5-20(27(6-7-28)22(18)25-19)21(29)14-8-16(30-2)10-17(9-14)31-3/h4-5,8-13,28-29H,6-7H2,1-3H3/b21-20+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair