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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM335693'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM335693
PNG
(US9737544, Compound 12)
Show SMILES COc1cc(OC)cc(c1)C(\O)=C1\CC=c2ncc(cc2=[N]1CCO)-c1cnn(C)c1
Show InChI InChI=1S/C23H25N4O4/c1-26-14-17(13-25-26)16-10-22-20(24-12-16)4-5-21(27(22)6-7-28)23(29)15-8-18(30-2)11-19(9-15)31-3/h4,8-14,28-29H,5-7H2,1-3H3/b23-21+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair