BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM335678'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM335678
PNG
(US9737544, Compound 7)
Show SMILES CNC(=O)\C=C(\c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 316n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair