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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM335681'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM335681
PNG
(US9737544, Compound 10)
Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C21H20N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12,21,26H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 63.1n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair