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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM335686'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM335686
PNG
(US9737544, Compound 18)
Show SMILES Cn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)c1cccc(O)c1
Show InChI InChI=1S/C19H14N4O2/c1-23-11-14(10-21-23)13-8-18-16(20-9-13)5-6-17(22-18)19(25)12-3-2-4-15(24)7-12/h2-11,24H,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair