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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM337333'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM337333
PNG
(4-(2-(3,5-Dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyr...)
Show SMILES COc1cc(CCc2cnc3[nH]c(cc3n2)-c2ccnc(c2)C#N)cc(OC)c1
Show InChI InChI=1S/C22H19N5O2/c1-28-18-7-14(8-19(10-18)29-2)3-4-16-13-25-22-21(26-16)11-20(27-22)15-5-6-24-17(9-15)12-23/h5-11,13H,3-4H2,1-2H3,(H,25,27)
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



Incyte Corporation; Incyte Holdings Corporation

US Patent


Assay Description
The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...


US Patent US9745311 (2017)

More data for this
Ligand-Target Pair