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Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM50197686'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50197686
PNG
(CHEMBL3956001)
Show SMILES Nc1c(cnn1-c1ccccc1Cl)C(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C18H13ClN4O/c19-13-6-2-4-8-16(13)23-18(20)12(10-21-23)17(24)15-9-11-5-1-3-7-14(11)22-15/h1-10,22H,20H2
PDB
MMDB

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Similars

Article
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assay


J Med Chem 59: 10586-10600 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01156
BindingDB Entry DOI: 10.7270/Q2ZS2ZGV
More data for this
Ligand-Target Pair