Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM335684'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM335684 (US9737544, Compound 16) Show SMILES COc1cccc(c1)C(=O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H16N4O2/c1-24-12-15(11-22-24)14-9-19-17(21-10-14)6-7-18(23-19)20(25)13-4-3-5-16(8-13)26-2/h3-12H,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017)
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