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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM335689'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 4


(Homo sapiens (Human))
BDBM335689
PNG
(US9737544, Compound 23)
Show SMILES COc1cc(OC)cc(c1)C(=O)c1cc2cc(cnc2cn1)-c1cnn(C)c1
Show InChI InChI=1S/C21H18N4O3/c1-25-12-16(10-24-25)15-4-13-7-19(23-11-20(13)22-9-15)21(26)14-5-17(27-2)8-18(6-14)28-3/h4-12H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+4n/an/an/an/an/an/a



ASTEX THERAPEUTICS LIMITED

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9737544 (2017)

More data for this
Ligand-Target Pair