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Found 5 Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' and Ligand = 'BDBM50344080'
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human GPR40 expressed in CHO cells by SPA based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  306nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as [3H]IP3 production in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  104nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  349nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as [3H]IP3 production in presence of 0.4% serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  113nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed