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Found 4 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM50266575'
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM50266575(CHEMBL4085777 | US10323016, Example 14)
Affinity DataEC50:  7.70E+3nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50266575(CHEMBL4085777 | US10323016, Example 14)
Affinity DataEC50:  939nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM50266575(CHEMBL4085777 | US10323016, Example 14)
Affinity DataEC50:  7.75E+3nMAssay Description:Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50266575(CHEMBL4085777 | US10323016, Example 14)
Affinity DataEC50:  940nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails US Patent