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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 6' and Ligand = 'BDBM382114'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 6


(Homo sapiens (Human))
BDBM382114
PNG
(6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-N-(2-(di...)
Show SMILES CC(C)Nc1ncc(nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)N(C)CCN(C)C
Show InChI InChI=1S/C24H34F2N6O2/c1-16(2)28-22-23(29-20(15-27-22)24(33)31(5)13-12-30(3)4)32-10-8-18(9-11-32)34-21-7-6-17(25)14-19(21)26/h6-7,14-16,18H,8-13H2,1-5H3,(H,27,28)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.72E+5n/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...


US Patent US10273225 (2019)


BindingDB Entry DOI: 10.7270/Q24X5B3J
More data for this
Ligand-Target Pair
G-protein coupled receptor 6


(Homo sapiens (Human))
BDBM382114
PNG
(6-(4-(2,4-difluorophenoxy)piperidin-1-yl)-N-(2-(di...)
Show SMILES CC(C)Nc1ncc(nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)N(C)CCN(C)C
Show InChI InChI=1S/C24H34F2N6O2/c1-16(2)28-22-23(29-20(15-27-22)24(33)31(5)13-12-30(3)4)32-10-8-18(9-11-32)34-21-7-6-17(25)14-19(21)26/h6-7,14-16,18H,8-13H2,1-5H3,(H,27,28)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.72E+5n/an/an/an/a



Takeda Pharmaceutical Co., Ltd

US Patent


Assay Description
This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...


US Patent US10000468 (2018)


BindingDB Entry DOI: 10.7270/Q23R0W71
More data for this
Ligand-Target Pair