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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50242351'
TargetGTPase KRas(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242351(CHEMBL4074790)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of biotinylated wild-type K-Ras (unknown origin) assessed as inhibition of human SOS1 (564 to 1049 residues)-mediated BODIPY-GDP-GTP excha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed