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Found 3 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50007223'
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007223(CHEMBL3238215)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]-glucagon from recombinant human GCGR expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007223(CHEMBL3238215)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-stimulated cAMP production preincubated for 30 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007223(CHEMBL3238215)
Affinity DataIC50:  110nMAssay Description:Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed