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Found 4 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50075788'
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  40nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  421nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  460nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  990nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed