Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50048345'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataKi:  1.97nMAssay Description:Binding Assay (I):In order to assess the affinity of test compounds for the human glucocorticoid receptor, a commercially available kit was used (Glu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataKi:  2nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataEC50:  211nMAssay Description:Agonist activity at glucocorticoid receptor in human whole blood assessed as inhibition of LPS-induced TNF production incubated for 20 hrs prior to L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataEC50:  12nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as E-selectin transrepression by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataEC50:  17nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as AP-1 transrepression by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50048345(CHEMBL3315067 | US9593113, Example 46)
Affinity DataEC50:  113nMAssay Description:Agonist activity at glucocorticoid receptor in human HeLa cells assessed as NP-1 transactivation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed