Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Glucose-6-phosphate 1-dehydrogenase' and Ligand = 'BDBM50223368'
TargetGlucose-6-phosphate 1-dehydrogenase(Trypanosoma brucei)
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei G6PDH using NADP as substrate by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Trypanosoma brucei)
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Trypanosoma brucei G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Universidade De SãO Paulo

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataIC50:  2.49E+4nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed