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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucosylceramidase' and Ligand = 'BDBM18437'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucosylceramidase


(Homo sapiens (Human))
BDBM18437
PNG
(Aminoquinoline compound, 22 | N-{2-[(3-chloropheny...)
Show SMILES CC1CCC(CC1)C(=O)Nc1ccc2nc(Nc3cccc(Cl)c3)cc(C)c2c1
Show InChI InChI=1S/C24H26ClN3O/c1-15-6-8-17(9-7-15)24(29)27-20-10-11-22-21(14-20)16(2)12-23(28-22)26-19-5-3-4-18(25)13-19/h3-5,10-15,17H,6-9H2,1-2H3,(H,26,28)(H,27,29)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
1.22E+5 -22.0n/an/an/an/an/a5.921



NIH



Assay Description
Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...


Proc Natl Acad Sci U S A 104: 13192-7 (2007)


Article DOI: 10.1073/pnas.0705637104
BindingDB Entry DOI: 10.7270/Q2V1232M
More data for this
Ligand-Target Pair