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Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50344250'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344250(CHEMBL1779003 | N-((5-(4-fluoro-2-methoxyphenyl)py...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344250(CHEMBL1779003 | N-((5-(4-fluoro-2-methoxyphenyl)py...)
Affinity DataIC50:  770nMAssay Description:Antagonist activity at human NR2B expressed in HEK293 cells assessed as glutamate-induced changes in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed