Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50344260'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 116nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
AstraZeneca Pharmaceuticals
Curated by ChEMBL
AstraZeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 673nMAssay Description:Antagonist activity at human NR2B expressed in HEK293 cells assessed as glutamate-induced changes in intracellular calcium concentrationMore data for this Ligand-Target Pair