BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate-NMDA' and Ligand = 'BDBM50005048'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate-NMDA


(RAT)
BDBM50005048
PNG
(5,7-Dichloro-4-[(2,3-dihydro-indole-1-carbonyl)-am...)
Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)N2CCc3ccccc23)c2c(Cl)cc(Cl)cc2N1
Show InChI InChI=1S/C19H17Cl2N3O3/c20-11-7-12(21)17-13(8-11)22-15(18(25)26)9-14(17)23-19(27)24-6-5-10-3-1-2-4-16(10)24/h1-4,7-8,14-15,22H,5-6,9H2,(H,23,27)(H,25,26)/t14-,15+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.


J Med Chem 35: 1954-68 (1992)


Article DOI: 10.1021/jm00089a004
BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair