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Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM404693'
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM404693(N-(pyridin-2-ylmethyl)-5-[4-(6- {2-[3-(trifluorome...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM404693(N-(pyridin-2-ylmethyl)-5-[4-(6- {2-[3-(trifluorome...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM404693(N-(pyridin-2-ylmethyl)-5-[4-(6- {2-[3-(trifluorome...)
Affinity DataIC50: <100nMAssay Description:Inhibition of GAC (unknown origin) using 1 mM glutamine as substrate preincubated for 10 mins by resorufin dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed