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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Ligand = 'BDBM202322'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202322
PNG
(US9238619, 53)
Show SMILES CN(CCOc1cc(ccc1F)C1(Cc2ccccc2)CN(C)C1)S(=O)(=O)c1cn(C)cn1
Show InChI InChI=1S/C24H29FN4O3S/c1-27-15-23(26-18-27)33(30,31)29(3)11-12-32-22-13-20(9-10-21(22)25)24(16-28(2)17-24)14-19-7-5-4-6-8-19/h4-10,13,15,18H,11-12,14,16-17H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair