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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Ligand = 'BDBM327827'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM327827
PNG
((R)-2-(4-benzhydryl-2-methylpiperazin-1-yl)acetic ...)
Show SMILES C[C@@H]1CN(CCN1CC(O)=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C20H24N2O2/c1-16-14-22(13-12-21(16)15-19(23)24)20(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,16,20H,12-15H2,1H3,(H,23,24)/t16-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 1.51n/an/an/an/an/an/a



AMGEN INC.

US Patent


Assay Description
This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...


US Patent US9663476 (2017)


Article DOI: 10.1016/j.bmcl.2009.04.124
BindingDB Entry DOI: 10.7270/Q2KK9DWS
More data for this
Ligand-Target Pair