BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM385209'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM385209
PNG
(US10287267, Compound 433 | US10508099, Compound 43...)
Show SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1
Show InChI InChI=1S/C16H15N5O/c1-21-9-14(19-20-21)11-4-5-12-8-17-15(7-13(12)6-11)18-16(22)10-2-3-10/h4-10H,2-3H2,1H3,(H,17,18,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...


US Patent US10287267 (2019)


BindingDB Entry DOI: 10.7270/Q2MS3W3C
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM385209
PNG
(US10287267, Compound 433 | US10508099, Compound 43...)
Show SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1
Show InChI InChI=1S/C16H15N5O/c1-21-9-14(19-20-21)11-4-5-12-8-17-15(7-13(12)6-11)18-16(22)10-2-3-10/h4-10H,2-3H2,1H3,(H,17,18,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
GSK3B: This is a non-radioactive assay using fluorescence resonance energy transfer (FRET) between coumarin and fluorescein to detect kinase activity...


US Patent US10556885 (2020)


BindingDB Entry DOI: 10.7270/Q2ZW1P9Z
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM385209
PNG
(US10287267, Compound 433 | US10508099, Compound 43...)
Show SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1
Show InChI InChI=1S/C16H15N5O/c1-21-9-14(19-20-21)11-4-5-12-8-17-15(7-13(12)6-11)18-16(22)10-2-3-10/h4-10H,2-3H2,1H3,(H,17,18,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...


US Patent US10508099 (2019)


BindingDB Entry DOI: 10.7270/Q2DJ5J0C
More data for this
Ligand-Target Pair