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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM459181'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM459181
PNG
(US10759799, Compound 2)
Show SMILES O=C1CCc2cccc(c2)-c2nccc3[nH]c(nc23)-c2n[nH]c3ccc(cc23)-c2cncc(N1)c2
Show InChI InChI=1S/C27H19N7O/c35-23-7-4-15-2-1-3-17(10-15)24-26-22(8-9-29-24)31-27(32-26)25-20-12-16(5-6-21(20)33-34-25)18-11-19(30-23)14-28-13-18/h1-3,5-6,8-14H,4,7H2,(H,30,35)(H,31,32)(H,33,34)
PDB
MMDB

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US Patent
n/an/an/an/a 1n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...


US Patent US10759799 (2020)

More data for this
Ligand-Target Pair