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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM459188'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM459188
PNG
(US10759799, Compound 10)
Show SMILES C1NCc2cncc(c2)-c2ccc3[nH]nc(-c4nc5c(cccc5[nH]4)-c4cccc1c4)c3c2
Show InChI InChI=1S/C27H20N6/c1-3-16-9-19(4-1)21-5-2-6-24-25(21)31-27(30-24)26-22-11-18(7-8-23(22)32-33-26)20-10-17(13-28-12-16)14-29-15-20/h1-11,14-15,28H,12-13H2,(H,30,31)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...


US Patent US10759799 (2020)

More data for this
Ligand-Target Pair