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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM484728'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM484728
PNG
(US10934297, Compound 141)
Show SMILES CN1CCC(CC1)n1cc(NC(=O)c2n[nH]c3ccc(cc23)-c2cnn(C)c2)cn1
Show InChI InChI=1S/C21H24N8O/c1-27-7-5-17(6-8-27)29-13-16(11-23-29)24-21(30)20-18-9-14(3-4-19(18)25-26-20)15-10-22-28(2)12-15/h3-4,9-13,17H,5-8H2,1-2H3,(H,24,30)(H,25,26)
PDB
MMDB

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KEGG

UniProtKB/SwissProt
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4n/an/an/an/a



Samumed, LLC

US Patent


Assay Description
GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...


US Patent US10934297 (2021)

More data for this
Ligand-Target Pair