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Found 3 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM498731'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498731((1S,3R)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  1.85nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498731((1S,3R)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  1.85nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498731((1S,3R)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed