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Found 3 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM405274'
TargetGonadotropin-releasing hormone receptor(Rabbit)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405274(1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)met...)
Affinity DataIC50:  0.570nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405274(1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)met...)
Affinity DataIC50:  4.95nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM405274(1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)met...)
Affinity DataIC50:  4.95nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In DepthDetails US Patent