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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HCV NS5B Mutant(S282T)' and Ligand = 'BDBM347265'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HCV NS5B Mutant(S282T)


(Hepatitis C virus genotype 1b (isolate Japanese) (...)
BDBM347265
PNG
(US10202411, Compound 327)
Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O
PDB
MMDB

B.MOAD
GoogleScholar
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a<250n/an/an/an/an/an/a



IDENIX PHARMACEUTICALS LLC

US Patent


Assay Description
Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...


US Patent US10202411 (2019)

More data for this
Ligand-Target Pair