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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108290'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108290
PNG
(US8604046, 70)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC3)C(=O)C3CCOCC3)C2=O)c(F)c1
Show InChI InChI=1S/C30H43FN4O3/c1-22-4-2-13-34(22)25-7-15-33(21-25)24-5-6-27(26(31)20-24)35-14-3-10-30(29(35)37)11-16-32(17-12-30)28(36)23-8-18-38-19-9-23/h5-6,20,22-23,25H,2-4,7-19,21H2,1H3/t22-,25-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair