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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108292'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108292
PNG
(US8604046, 72)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(CC4CCCCC4)CC3)C2=O)c(C)c1
Show InChI InChI=1/C32H50N4O/c1-25-22-28(34-19-13-29(24-34)35-17-6-8-26(35)2)11-12-30(25)36-18-7-14-32(31(36)37)15-20-33(21-16-32)23-27-9-4-3-5-10-27/h11-12,22,26-27,29H,3-10,13-21,23-24H2,1-2H3/t26-,29-/s2
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.200n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair