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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108294'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108294
PNG
(US8604046, 74)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC2)C2CCOCC2)C1=O
Show InChI InChI=1/C29H44N4O2/c1-23-4-2-15-32(23)27-9-17-31(22-27)24-5-7-26(8-6-24)33-16-3-12-29(28(33)34)13-18-30(19-14-29)25-10-20-35-21-11-25/h5-8,23,25,27H,2-4,9-22H2,1H3/t23-,27-/s2
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.0400n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair