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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108302'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108302
PNG
(US8604046, 82)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(F)c1
Show InChI InChI=1S/C29H43FN4O3/c1-21-7-5-6-14-33(21)23-10-15-32(20-23)22-8-9-25(24(30)19-22)34-18-13-29(26(34)35)11-16-31(17-12-29)27(36)37-28(2,3)4/h8-9,19,21,23H,5-7,10-18,20H2,1-4H3/t21-,23-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
4.30n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair