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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108305'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108305
PNG
(US8604046, 85)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1
Show InChI InChI=1S/C24H35FN4O/c1-18-3-2-13-28(18)19-6-14-27(15-7-19)20-4-5-22(21(25)17-20)29-16-10-24(23(29)30)8-11-26-12-9-24/h4-5,17-19,26H,2-3,6-16H2,1H3/t18-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair