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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108317'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108317
PNG
(US8604046, 97)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCN(CC4CCCCC4)CC3)C2=O)c(c1)C(F)(F)F
Show InChI InChI=1S/C32H47F3N4O/c1-24-7-5-6-16-38(24)27-12-17-37(23-27)26-10-11-29(28(21-26)32(33,34)35)39-20-15-31(30(39)40)13-18-36(19-14-31)22-25-8-3-2-4-9-25/h10-11,21,24-25,27H,2-9,12-20,22-23H2,1H3/t24-,27-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.150n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair