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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335429'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335429
PNG
(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-(2-methylpropyl)...)
Show SMILES CC(C)CNc1cc(ccn1)N1CC[C@@H](N)C1
Show InChI InChI=1S/C13H22N4/c1-10(2)8-16-13-7-12(3-5-15-13)17-6-4-11(14)9-17/h3,5,7,10-11H,4,6,8-9,14H2,1-2H3,(H,15,16)/t11-/m1/s1
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
3.5n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)


Article DOI: 10.1021/jm060807n
More data for this
Ligand-Target Pair