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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335439'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335439
PNG
(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-cyclopropylpyrim...)
Show SMILES N[C@@H]1CCN(C1)c1ccnc(NC2CC2)n1
Show InChI InChI=1S/C11H17N5/c12-8-4-6-16(7-8)10-3-5-13-11(15-10)14-9-1-2-9/h3,5,8-9H,1-2,4,6-7,12H2,(H,13,14,15)/t8-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
138n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)

More data for this
Ligand-Target Pair