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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335443'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335443
PNG
(Bicyclo[2.2.1]hept-2-yl-(4-piperazin-1-yl-pyrimidi...)
Show SMILES C1CC2CC1CC2Nc1nccc(n1)N1CCNCC1
Show InChI InChI=1S/C15H23N5/c1-2-12-9-11(1)10-13(12)18-15-17-4-3-14(19-15)20-7-5-16-6-8-20/h3-4,11-13,16H,1-2,5-10H2,(H,17,18,19)
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
240n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)


Article DOI: 10.1021/jm060807n
More data for this
Ligand-Target Pair