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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335446'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335446
PNG
(4-(3-Aminoazetidin-1-yl)-N-(1-methylethyl)pyrimidi...)
Show SMILES CC(C)Nc1nccc(n1)N1CC(N)C1
Show InChI InChI=1S/C10H17N5/c1-7(2)13-10-12-4-3-9(14-10)15-5-8(11)6-15/h3-4,7-8H,5-6,11H2,1-2H3,(H,12,13,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
68.9n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)

More data for this
Ligand-Target Pair