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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335449'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335449
PNG
(5-[(3R)-3-(Methylamino)pyrrolidin-1-yl]-N-[(1S,2S,...)
Show SMILES CN[C@@H]1CCN(C1)c1cnnc(NC2C[C@H]3C[C@@H]([C@@H]2C)C3(C)C)c1
Show InChI InChI=1S/C19H31N5/c1-12-16-7-13(19(16,2)3)8-17(12)22-18-9-15(10-21-23-18)24-6-5-14(11-24)20-4/h9-10,12-14,16-17,20H,5-8,11H2,1-4H3,(H,22,23)/t12-,13+,14+,16-,17?/m0/s1
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GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
5.90n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)


Article DOI: 10.1021/jm060807n
More data for this
Ligand-Target Pair