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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335450'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335450
PNG
(N-Cyclohexyl-5-[(3R)-3-(methylamino)pyrrolidin-1-y...)
Show SMILES CN[C@@H]1CCN(C1)c1cnnc(NC2CCCCC2)c1
Show InChI InChI=1S/C15H25N5/c1-16-13-7-8-20(11-13)14-9-15(19-17-10-14)18-12-5-3-2-4-6-12/h9-10,12-13,16H,2-8,11H2,1H3,(H,18,19)/t13-/m1/s1
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
4.80n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)

More data for this
Ligand-Target Pair