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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM335452'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335452
PNG
(N-Butyl-5-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyr...)
Show SMILES CCCCNc1cc(cnn1)N1CC[C@H](C1)NC
Show InChI InChI=1S/C13H23N5/c1-3-4-6-15-13-8-12(9-16-17-13)18-7-5-11(10-18)14-2/h8-9,11,14H,3-7,10H2,1-2H3,(H,15,17)/t11-/m1/s1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
US Patent
31n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)


Article DOI: 10.1021/jm060807n
More data for this
Ligand-Target Pair