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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM182757'
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182757(US9145412, Table 1, Compound 23)
Affinity DataIC50:  4nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM182757(US9145412, Table 1, Compound 23)
Affinity DataIC50:  7nMAssay Description:Inhibition of HDAC1 (unknown origin) using acetyl-lysine tripeptide as substrate preincubated for 10 mins followed by substrate addition and shaken f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed